Pulmonary blood flow distribution during partial liquid ventilation
نویسندگان
چکیده
منابع مشابه
Changes in pulmonary blood flow during gaseous and partial liquid ventilation in experimental acute lung injury.
BACKGROUND It has been proposed that partial liquid ventilation (PLV) causes a compression of the pulmonary vasculature by the dense perfluorocarbons and a subsequent redistribution of pulmonary blood flow from dorsal to better-ventilated middle and ventral lung regions, thereby improving arterial oxygenation in situations of acute lung injury. METHODS After induction of acute lung injury by ...
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Replacing gas in the lung with perfluorocarbon fluids (PFC) and periodically ventilating with a gas [partial liquid ventilation (PLV)] has been shown to improve oxygenation in models of respiratory distress syndrome. We hypothesized that the addition of PFC to healthy lungs would result in shunt, diffusion impairment, and increased ventilation-perfusion (VA/Q) heterogeneity. Previously, Mates e...
متن کاملPartial liquid ventilation.
Correspondence: B. Lachmann, Dept of Anesthesiology (Room Ee 2393), Erasmus University Rotterdam, Postbox 1738, 3000 DR Rotterdam, The Netherlands. There is strong indication that modes of ventilation that lead to repeated closure and opening of surfactantdeficient alveoli can induce severe functional and histological lung damage [1]. New modes of ventilation are directed at prevention of lung ...
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A lumped two-compartment mathematical model of respiratory mechanics incorporating gas exchange and pulmonary circulation is utilized to analyze the effects of square, descending and ascending inspiratory flow waveforms during mechanical ventilation. The effects on alveolar volume variation, alveolar pressure, airway pressure, gas exchange rate, and expired gas species concentration are evaluat...
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ژورنال
عنوان ژورنال: Journal of Applied Physiology
سال: 1998
ISSN: 8750-7587,1522-1601
DOI: 10.1152/jappl.1998.84.5.1540